Records found: 423
Transcriptional networks inferred from molecular signatures of breast cancer.Tongbai, R., Idelman, G., Nordgard, S.H., Cui, W., Jacobs, J.L., Haggerty, C.M., Chanock, S.J., Borresen-Dale, A.L., Livingston, G., Shaunessy, P., Chiang, C.H., Kristensen, V.N., Bilke, S., and Gardner, K.
Am J Pathol 172, 495-509; 2008.
PubMed
EzArray: A web-based highly automated Affymetrix expression array data management and analysis system.Zhu, Y., Zhu, Y., and Xu, W.
BMC bioinformatics 9, 46; 2008.
PubMedA combined approach identifies a limited number of new thyroid hormone target genes in post-natal mouse cerebellum.Quignodon, L., Grijota-Martinez, C., Compe, E., Guyot, R., Allioli, N., Laperriere, D., Walker, R., Meltzer, P., Mader, S., Samarut, J., and Flamant, F.
J Mol Endocrinol 39, 17-28; 2007.
PubMedGEOquery: a bridge between the Gene Expression Omnibus (GEO) and BioConductor.Davis, S., and Meltzer, P.S.
Bioinformatics (Oxford, England), ; 2007.
PubMedIdentification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.Birney, E., Stamatoyannopoulos, J.A., Dutta, A., Guigo, R., Gingeras, T.R., Margulies, E.H., Weng, Z., Snyder, M., Dermitzakis, E.T., Thurman, R.E., Kuehn, M.S., Taylor, C.M., Neph, S., Koch, C.M., Asthana, S., Malhotra, A., Adzhubei, I., Greenbaum, J.A., Andrews, R.M., Flicek, P., Boyle, P.J., Cao, H., Carter, N.P., Clelland, G.K., Davis, S., Day, N., Dhami, P., Dillon, S.C., Dorschner, M.O., Fiegler, H., Giresi, P.G., Goldy, J., Hawrylycz, M., Haydock, A., Humbert, R., James, K.D., Johnson, B.E., Johnson, E.M., Frum, T.T., Rosenzweig, E.R., Karnani, N., Lee, K., Lefebvre, G.C., Navas, P.A., Neri, F., Parker, S.C., Sabo, P.J., Sandstrom, R., Shafer, A., Vetrie, D., Weaver, M., Wilcox, S., Yu, M., Collins, F.S., Dekker, J., Lieb, J.D., Tullius, T.D., Crawford, G.E., Sunyaev, S., Noble, W.S., Dunham, I., Denoeud, F., Reymond, A., Kapranov, P., Rozowsky, J., Zheng, D., Castelo, R., Frankish, A., Harrow, J., Ghosh, S., Sandelin, A., Hofacker, I.L., Baertsch, R., Keefe, D., Dike, S., Cheng, J., Hirsch, H.A., Sekinger, E.A., Lagarde, J., Abril, J.F., Shahab, A., Flamm, C., Fried, C., Hackermuller, J., Hertel, J., Lindemeyer, M., Missal, K., Tanzer, A., Washietl, S., Korbel, J., Emanuelsson, O., Pedersen, J.S., Holroyd, N., Taylor, R., Swarbreck, D., Matthews, N., Dickson, M.C., Thomas, D.J., Weirauch, M.T., Gilbert, J., Drenkow, J., Bell, I., Zhao, X., Srinivasan, K.G., Sung, W.K., Ooi, H.S., Chiu, K.P., Foissac, S., Alioto, T., Brent, M., Pachter, L., Tress, M.L., Valencia, A., Choo, S.W., Choo, C.Y., Ucla, C., Manzano, C., Wyss, C., Cheung, E., Clark, T.G., Brown, J.B., Ganesh, M., Patel, S., Tammana, H., Chrast, J., Henrichsen, C.N., Kai, C., Kawai, J., Nagalakshmi, U., Wu, J., Lian, Z., Lian, J., Newburger, P., Zhang, X., Bickel, P., Mattick, J.S., Carninci, P., Hayashizaki, Y., Weissman, S., Hubbard, T., Myers, R.M., Rogers, J., Stadler, P.F., Lowe, T.M., Wei, C.L., Ruan, Y., Struhl, K., Gerstein, M., Antonarakis, S.E., Fu, Y., Green, E.D., Karaoz, U., Siepel, A., Taylor, J., Liefer, L.A., Wetterstrand, K.A., Good, P.J., Feingold, E.A., Guyer, M.S., Cooper, G.M., Asimenos, G., Dewey, C.N., Hou, M., Nikolaev, S., Montoya-Burgos, J.I., Loytynoja, A., Whelan, S., Pardi, F., Massingham, T., Huang, H., Zhang, N.R., Holmes, I., Mullikin, J.C., Ureta-Vidal, A., Paten, B., Seringhaus, M., Church, D., Rosenbloom, K., Kent, W.J., Stone, E.A., Batzoglou, S., Goldman, N., Hardison, R.C., Haussler, D., Miller, W., Sidow, A., Trinklein, N.D., Zhang, Z.D., Barrera, L., Stuart, R., King, D.C., Ameur, A., Enroth, S., Bieda, M.C., Kim, J., Bhinge, A.A., Jiang, N., Liu, J., Yao, F., Vega, V.B., Lee, C.W., Ng, P., Shahab, A., Yang, A., Moqtaderi, Z., Zhu, Z., Xu, X., Squazzo, S., Oberley, M.J., Inman, D., Singer, M.A., Richmond, T.A., Munn, K.J., Rada-Iglesias, A., Wallerman, O., Komorowski, J., Fowler, J.C., Couttet, P., Bruce, A.W., Dovey, O.M., Ellis, P.D., Langford, C.F., Nix, D.A., Euskirchen, G., Hartman, S., Urban, A.E., Kraus, P., Van Calcar, S., Heintzman, N., Kim, T.H., Wang, K., Qu, C., Hon, G., Luna, R., Glass, C.K., Rosenfeld, M.G., Aldred, S.F., Cooper, S.J., Halees, A., Lin, J.M., Shulha, H.P., Zhang, X., Xu, M., Haidar, J.N., Yu, Y., Ruan, Y., Iyer, V.R., Green, R.D., Wadelius, C., Farnham, P.J., Ren, B., Harte, R.A., Hinrichs, A.S., Trumbower, H., Clawson, H., Hillman-Jackson, J., Zweig, A.S., Smith, K., Thakkapallayil, A., Barber, G., Kuhn, R.M., Karolchik, D., Armengol, L., Bird, C.P., de Bakker, P.I., Kern, A.D., Lopez-Bigas, N., Martin, J.D., Stranger, B.E., Woodroffe, A., Davydov, E., Dimas, A., Eyras, E., Hallgrimsdottir, I.B., Huppert, J., Zody, M.C., Abecasis, G.R., Estivill, X., Bouffard, G.G., Guan, X., Hansen, N.F., Idol, J.R., Maduro, V.V., Maskeri, B., McDowell, J.C., Park, M., Thomas, P.J., Young, A.C., Blakesley, R.W., Muzny, D.M., Sodergren, E., Wheeler, D.A., Worley, K.C., Jiang, H., Weinstock, G.M., Gibbs, R.A., Graves, T., Fulton, R., Mardis, E.R., Wilson, R.K., Clamp, M., Cuff, J., Gnerre, S., Jaffe, D.B., Chang, J.L., Lindblad-Toh, K., Lander, E.S., Koriabine, M., Nefedov, M., Osoegawa, K., Yoshinaga, Y., Zhu, B., and de Jong, P.J.
Nature 447, 799-816; 2007.
PubMedModeling synovial sarcoma: timing is everything.Davis, S.R., and Meltzer, P.S.
Cancer Cell 11, 305-307; 2007.
PubMedExpression of the cytoskeleton linker protein ezrin in human cancers.Bruce, B., Khanna, G., Ren, L., Landberg, G., Jirstrom, K., Powell, C., Borczuk, A., Keller, E.T., Wojno, K.J., Meltzer, P., Baird, K., McClatchey, A., Bretscher, A., Hewitt, S.M., and Khanna, C.
Clin Exp Metastasis 24, 69-78; 2007.
PubMedClaudin-1 overexpression in melanoma is regulated by PKC and contributes to melanoma cell motility.Leotlela, P.D., Wade, M.S., Duray, P.H., Rhode, M.J., Brown, H.F., Rosenthal, D.T., Dissanayake, S.K., Earley, R., Indig, F.E., Nickoloff, B.J., Taub, D.D., Kallioniemi, O.P., Meltzer, P., Morin, P.J., and Weeraratna, A.T.
Oncogene 26, 3846-3856; 2007.
PubMedZoom-in comparative genomic hybridisation arrays for the characterisation of variable breakpoint contiguous gene syndromes.Johnston, J.J., Walker, R.L., Davis, S., Facio, F., Turner, J.T., Bick, D.P., Daentl, D.L., Ellison, J.W., Meltzer, P.S., and Biesecker, L.G.
J Med Genet 44, e59; 2007.
PubMedDetection of novel amplicons in prostate cancer by comprehensive genomic profiling of prostate cancer cell lines using oligonucleotide-based arrayCGH.Kamradt, J., Jung, V., Wahrheit, K., Tolosi, L., Rahnenfuehrer, J., Schilling, M., Walker, R., Davis, S., Stoeckle, M., Meltzer, P., and Wullich, B.
PLoS ONE 2, e769; 2007.
PubMedConstitutive Fms-like tyrosine kinase 3 activation results in specific changes in gene expression in myeloid leukaemic cells.Kim, K.T., Baird, K., Davis, S., Piloto, O., Levis, M., Li, L., Chen, P., Meltzer, P., and Small, D.
Br J Haematol 138, 603-615; 2007.
PubMedA single IGF1 allele is a major determinant of small size in dogs.Sutter, N.B., Bustamante, C.D., Chase, K., Gray, M.M., Zhao, K., Zhu, L., Padhukasahasram, B., Karlins, E., Davis, S., Jones, P.G., Quignon, P., Johnson, G.S., Parker, H.G., Fretwell, N., Mosher, D.S., Lawler, D.F., Satyaraj, E., Nordborg, M., Lark, K.G., Wayne, R.K., and Ostrander, E.A.
Science 316, 112-115; 2007.
PubMedThe Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition.Dissanayake, S.K., Wade, M., Johnson, C.E., O'Connell, M.P., Leotlela, P.D., French, A.D., Shah, K.V., Hewitt, K.J., Rosenthal, D.T., Indig, F.E., Jiang, Y., Nickoloff, B.J., Taub, D.D., Trent, J.M., Moon, R.T., Bittner, M., and Weeraratna, A.T.
The Journal of biological chemistry 282, 17259-17271; 2007.
PubMedA Cell Proliferation and Chromosomal Instability Signature in Anaplastic Thyroid Carcinoma.Salvatore, G., Nappi, T.C., Salerno, P., Jiang, Y., Garbi, C., Ugolini, C., Miccoli, P., Basolo, F., Castellone, M.D., Cirafici, A.M., Melillo, R.M., Fusco, A., Bittner, M.L., and Santoro, M.
Cancer research 67, ; 2007.
PubMedBP1 transcriptionally activates bcl-2 and inhibits TNFalpha-induced cell death in MCF7 breast cancer cells.Stevenson, H.S., Fu, S.W., Pinzone, J.J., Rheey, J., Simmens, S.J., and Berg, P.E.
Breast Cancer Res 9, R60; 2007.
PubMedCharacterization of mismatch and high-signal intensity probes associated with Affymetrix genechips.Wang, Y., Miao, Z.H., Pommier, Y., Kawasaki, E.S., and Player, A.
Bioinformatics (Oxford, England) 23, 2088-2095; 2007.
PubMedManufacturing of microarrays.Petersen, D.W., and Kawasaki, E.S.
Advances in experimental medicine and biology 593, 1-11; 2007.
PubMedNonclassic functions of human topoisomerase I: genome-wide and pharmacologic analyses.Miao, Z.H., Player, A., Shankavaram, U., Wang, Y.H., Zimonjic, D.B., Lorenzi, P.L., Liao, Z.Y., Liu, H., Shimura, T., Zhang, H.L., Meng, L.H., Zhang, Y.W., Kawasaki, E.S., Popescu, N.C., Aladjem, M.I., Goldstein, D.J., Weinstein, J.N., and Pommier, Y.
Cancer research 67, 8752-8761; 2007.
PubMedCyclin-dependent kinase 5 differentially regulates the transcriptional activity of the glucocorticoid receptor through phosphorylation: clinical implications for the nervous system response to glucocorticoids and stress.Kino, T., Ichijo, T., Amin, N.D., Kesavapany, S., Wang, Y., Kim, N., Rao, S., Player, A., Zheng, Y.L., Garabedian, M.J., Kawasaki, E., Pant, H.C., and Chrousos, G.P.
Molecular endocrinology (Baltimore, Md 21, 1552-1568; 2007.
PubMedIdentification of arsenic-binding proteins in human breast cancer cells.Zhang, X., Yang, F., Shim, J.Y., Kirk, K.L., Anderson, D.E., and Chen, X.
Cancer letters 255, 95-106; 2007.
PubMedGlobal expression analysis of prostate cancer-associated stroma and epithelia.Richardson, A.M., Woodson, K., Wang, Y., Rodriguez-Canales, J., Erickson, H.S., Tangrea, M.A., Novakovic, K., Gonzalez, S., Velasco, A., Kawasaki, E.S., Emmert-Buck, M.R., Chuaqui, R.F., Player, A., Keenan, J., Liang, Y., and Clynes, M.
Diagn Mol In press, ; 2007.
PubMedGene Expression Analysis of RNA Purified From Embryonic Stem Cells And Embryoidal Body Derived Cells Using A High-Throughput Microarray Platform.Player, A., Wang, Y., Rao, M., and Kawasaki, E.S.
In: Current Protocols. John Wiley & Sons, Inc., ; 2007.
Interagency White Paper on Prion Science.Edelman, D.C.
Cyril Gay and Marcus Kehrli, editors. 2007.
Meleady P and Clynes M. Co-ordinate upregulation of gene expression at the transcriptional level during BrdU-induced differentiation of DLKP lung cells may involve the transcription factor GATA-3.Doolan, P., Barron, N., and Liang, Y.
Differentiation Submitted, ; 2007.
PubMedChromosome 8 BAC array comparative genomic hybridization and expression analysis identify amplification and overexpression of TRMT12 in breast cancer.Rodriguez, V., Chen, Y., Elkahloun, A., Dutra, A., Pak, E., and Chandrasekharappa, S.
Genes, chromosomes & cancer 46, 694-707; 2007.
PubMed |
SupplementGene expression profiling reveals potential biomarkers of human hepatocellular carcinoma.Jia, H.L., Ye, Q.H., Qin, L.X., Budhu, A., Forgues, M., Chen, Y., Liu, Y.K., Sun, H.C., Wang, L., Lu, H.Z., Shen, F., Tang, Z.Y., and Wang, X.W.
Clin Cancer Res 13, 1133-1139; 2007.
PubMedSensitive and specific method for detecting G protein-coupled receptor mRNAs.Hansen, A., Chen, Y., Inman, J.M., Phan, Q.N., Qi, Z.Q., Xiang, C.C., Palkovits, M., Cherman, N., Kuznetsov, S.A., Robey, P.G., Mezey, E., and Brownstein, M.J.
Nat Methods 4, 35-37; 2007.
PubMedMouse embryo fibroblasts lacking the tumor suppressor menin show altered expression of extracellular matrix protein genes.Ji, Y., Prasad, N.B., Novotny, E.A., Kaur, S., Elkahloun, A., Chen, Y., Zhang, R.Z., Chu, M.L., Agarwal, S.K., Marx, S.J., Collins, F.S., and Chandrasekharappa, S.C.
Mol Cancer Res 5, 1041-1051; 2007.
PubMedHuman X-Box binding protein-1 confers both estrogen independence and antiestrogen resistance in breast cancer cell lines.Gomez, B.P., Riggins, R.B., Shajahan, A.N., Klimach, U., Wang, A., Crawford, A.C., Zhu, Y., Zwart, A., Wang, M., and Clarke, R.
Faseb J, ; 2007.
PubMedAnalysis of comparative genomic hybridization data on cDNA microarrays.Bilke, S., and Khan, J.
Methods in molecular biology (Clifton, NJ 377, 175-186; 2007.
PubMedFunctional profiling of uncommon VCAM1 promoter polymorphisms prevalent in African American populations.Idelman, G., Taylor, J.G., Tongbai, R., Chen, R.A., Haggerty, C.M., Bilke, S., Chanock, S.J., and Gardner, K.
Human mutation 28, 824-829; 2007.
PubMedCredentialing preclinical pediatric xenograft models using gene expression and tissue microarray analysis.Whiteford, C.C., Bilke, S., Greer, B.T., Chen, Q., Braunschweig, T.A., Cenacchi, N., Wei, J.S., Smith, M.A., Houghton, P., Morton, C., Reynolds, C.P., Lock, R., Gorlick, R., Khanna, C., Thiele, C.J., Takikita, M., Catchpoole, D., Hewitt, S.M., and Khan, J.
Cancer research 67, 32-40; 2007.
PubMedProteomic expression profiling of thyroid neoplasms.Braunschweig, T., Kaserer, K., Chung, J.Y., Bilke, S., Krizman, D., Knezevic, V., and Hewitt, S.M.
PROTEOMICS - Clinical Applications 1, 8; 2007.
PubMedLipid defect underlies selective skin barrier impairment of an epidermal-specific deletion of Gata-3.de Guzman Strong, C., Wertz, P.W., Wang, C., Yang, F., Meltzer, P.S., Andl, T., Millar, S.E., Ho, I.C., Pai, S.Y., and Segre, J.A.
J Cell Biol 175, 661-670; 2006.
PubMedThe Synovial Sarcoma-Associated SS18-SSX2 Fusion Protein Induces Epigenetic Gene (De)Regulation.de Bruijn, D.R., Allander, S.V., van Dijk, A.H., Willemse, M.P., Thijssen, J., van Groningen, J.J., Meltzer, P.S., and Geurts van Kessel, A.
Cancer research 66, 9474-9482; 2006.
PubMedDNase-chip: a high-resolution method to identify DNase I hypersensitive sites using tiled microarrays.Crawford, G.E., Davis, S., Scacheri, P.C., Renaud, G., Halawi, M.J., Erdos, M.R., Green, R., Meltzer, P.S., Wolfsberg, T.G., and Collins, F.S.
Nat Methods 3, 503-509; 2006.
PubMedEwing's sarcoma: general insights from a rare model.Davis, S., and Meltzer, P.S.
Cancer Cell 9, 331-332; 2006.
PubMedMolecular and cytogenetic changes involved in the immortalization of nasopharyngeal epithelial cells by telomerase.Li, H.M., Man, C., Jin, Y., Deng, W., Yip, Y.L., Feng, H.C., Cheung, Y.C., Lo, K.W., Meltzer, P.S., Wu, Z.G., Kwong, Y.L., Yuen, A.P., and Tsao, S.W.
International journal of cancer 119, 1567-1576; 2006.
PubMedGenome-wide analysis of menin binding provides insights into MEN1 tumorigenesis.Scacheri, P.C., Davis, S., Odom, D.T., Crawford, G.E., Perkins, S., Halawi, M.J., Agarwal, S.K., Marx, S.J., Spiegel, A.M., Meltzer, P.S., and Collins, F.S.
PLoS Genet 2, e51; 2006.
PubMedThe epigenetic reprogramming of poorly aggressive melanoma cells by a metastatic microenvironment.Seftor, E.A., Meltzer, P.S., Kirschmann, D.A., Margaryan, N.V., Seftor, R.E., and Hendrix, M.J.
J Cell Mol Med 10, 174-196; 2006.
PubMedStatistics for ChIP-chip and DNase hypersensitivity experiments on NimbleGen arrays.Scacheri, P.C., Crawford, G.E., and Davis, S.
Methods Enzymol 411, 270-282; 2006.
PubMedAnalysis of the quality of contact-pin fabricated oligonucleotide microarrays.Yang, A.X., Mejido, J., Bhattacharya, B., Petersen, D., Han, J., Kawasaki, E.S., and Puri, R.K.
Molecular biotechnology 34, 303-315; 2006.
PubMedThe MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements.Shi, L., Reid, L.H., Jones, W.D., Shippy, R., Warrington, J.A., Baker, S.C., Collins, P.J., de Longueville, F., Kawasaki, E.S., Lee, K.Y., Luo, Y., Sun, Y.A., Willey, J.C., Setterquist, R.A., Fischer, G.M., Tong, W., Dragan, Y.P., Dix, D.J., Frueh, F.W., Goodsaid, F.M., Herman, D., Jensen, R.V., Johnson, C.D., Lobenhofer, E.K., Puri, R.K., Schrf, U., Thierry-Mieg, J., Wang, C., Wilson, M., Wolber, P.K., Zhang, L., Amur, S., Bao, W., Barbacioru, C.C., Lucas, A.B., Bertholet, V., Boysen, C., Bromley, B., Brown, D., Brunner, A., Canales, R., Cao, X.M., Cebula, T.A., Chen, J.J., Cheng, J., Chu, T.M., Chudin, E., Corson, J., Corton, J.C., Croner, L.J., Davies, C., Davison, T.S., Delenstarr, G., Deng, X., Dorris, D., Eklund, A.C., Fan, X.H., Fang, H., Fulmer-Smentek, S., Fuscoe, J.C., Gallagher, K., Ge, W., Guo, L., Guo, X., Hager, J., Haje, P.K., Han, J., Han, T., Harbottle, H.C., Harris, S.C., Hatchwell, E., Hauser, C.A., Hester, S., Hong, H., Hurban, P., Jackson, S.A., Ji, H., Knight, C.R., Kuo, W.P., LeClerc, J.E., Levy, S., Li, Q.Z., Liu, C., Liu, Y., Lombardi, M.J., Ma, Y., Magnuson, S.R., Maqsodi, B., McDaniel, T., Mei, N., Myklebost, O., Ning, B., Novoradovskaya, N., Orr, M.S., Osborn, T.W., Papallo, A., Patterson, T.A., Perkins, R.G., Peters, E.H., Peterson, R., Philips, K.L., Pine, P.S., Pusztai, L., Qian, F., Ren, H., Rosen, M., Rosenzweig, B.A., Samaha, R.R., Schena, M., Schroth, G.P., Shchegrova, S., Smith, D.D., Staedtler, F., Su, Z., Sun, H., Szallasi, Z., Tezak, Z., Thierry-Mieg, D., Thompson, K.L., Tikhonova, I., Turpaz, Y., Vallanat, B., Van, C., Walker, S.J., Wang, S.J., Wang, Y., Wolfinger, R., Wong, A., Wu, J., Xiao, C., Xie, Q., Xu, J., Yang, W., Zhang, L., Zhong, S., Zong, Y., and Slikker, W., Jr.
Nature biotechnology 24, 1151-1161; 2006.
PubMedComparisons between transcriptional regulation and RNA expression in human embryonic stem cell lines.Player, A., Wang, Y., Bhattacharya, B., Rao, M., Puri, R.K., and Kawasaki, E.S.
Stem cells and development 15, 315-323; 2006.
PubMedPerformance comparison of one-color and two-color platforms within the MicroArray Quality Control (MAQC) project.Patterson, T.A., Lobenhofer, E.K., Fulmer-Smentek, S.B., Collins, P.J., Chu, T.M., Bao, W., Fang, H., Kawasaki, E.S., Hager, J., Tikhonova, I.R., Walker, S.J., Zhang, L., Hurban, P., de Longueville, F., Fuscoe, J.C., Tong, W., Shi, L., and Wolfinger, R.D.
Nature biotechnology 24, 1140-1150; 2006.
PubMedThe end of the microarray Tower of Babel: will universal standards lead the way?Kawasaki, E.S.
J Biomol Tech 17, 200-206; 2006.
PubMedWnt-1 is dominant over neu in specifying mammary tumor expression profiles.Huang, S., Podsypanina, K., Chen, Y., Cai, W., Tsimelzon, A., Hilsenbeck, S., and Li, Y.
Technol Cancer Res Treat 5, 565-571; 2006.
PubMedGene expression profiling of human placentas from preeclamptic and normotensive pregnancies.Hansson, S.R., Chen, Y., Brodszki, J., Chen, M., Hernandez-Andrade, E., Inman, J.M., Kozhich, O.A., Larsson, I., Marsal, K., Medstrand, P., Xiang, C.C., and Brownstein, M.J.
Mol Hum Reprod 12, 169-179; 2006.
PubMedIdentification of molecular markers for endometriosis in blood lymphocytes by using deoxyribonucleic acid microarrays.Flores, I., Rivera, E., Mousses, S., Chen, Y., and Rozenblum, E.
Fertil Steril 85, 1676-1683; 2006.
PubMedA novel role of myosin VI in human prostate cancer.Dunn, T.A., Chen, S., Faith, D.A., Hicks, J.L., Platz, E.A., Chen, Y., Ewing, C.M., Sauvageot, J., Isaacs, W.B., De Marzo, A.M., and Luo, J.
Am J Pathol 169, 1843-1854; 2006.
PubMedGenome-wide mapping of DNase hypersensitive sites using massively parallel signature sequencing (MPSS).Crawford, G.E., Holt, I.E., Whittle, J., Webb, B.D., Tai, D., Davis, S., Margulies, E.H., Chen, Y., Bernat, J.A., Ginsburg, D., Zhou, D., Luo, S., Vasicek, T.J., Daly, M.J., Wolfsberg, T.G., and Collins, F.S.
Genome research 16, 123-131; 2006.
PubMedPrediction of venous metastases, recurrence, and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment.Budhu, A., Forgues, M., Ye, Q.H., Jia, H.L., He, P., Zanetti, K.A., Kammula, U.S., Chen, Y., Qin, L.X., Tang, Z.Y., and Wang, X.W.
Cancer Cell 10, 99-111; 2006.
PubMedExpression Technology – a Critical Review of the Nature, Performance, and Interpretation of Expression Micro arrays IEEE SPM review of white paper SPMGP.139, 2006. .Stafford, P., and Chen, Y.
In: IEEE SPM review of white paper SPMGP. IEEE, 139; 2006.
Microarray Data Analysis.Li, Y., and Chen, Y.
In: Microarray Data Analysis. Chemical Industry Publish, ; 2006.
Estrogen receptor alpha positive breast tumors and breast cancer cell lines share similarities in their transcriptome data structures.Zhu, Y., Wang, A., Liu, M.C., Zwart, A., Lee, R.Y., Gallagher, A., Wang, Y., Miller, W.R., Dixon, J.M., and Clarke, R.
International journal of oncology 29, 1581-1589; 2006.
PubMedExpression patterns among interferon regulatory factor-1, human X-box binding protein-1, nuclear factor kappa B, nucleophosmin, estrogen receptor-alpha and progesterone receptor proteins in breast cancer tissue microarrays.Zhu, Y., Singh, B., Hewitt, S., Liu, A., Gomez, B., Wang, A., and Clarke, R.
International journal of oncology 28, 67-76; 2006.
PubMedIncreased WSB1 copy number correlates with its over-expression which associates with increased survival in neuroblastoma.Chen, Q.R., Bilke, S., Wei, J.S., Greer, B.T., Steinberg, S.M., Westermann, F., Schwab, M., and Khan, J.
Genes, chromosomes & cancer 45, 856-862; 2006.
PubMedBioMart and Bioconductor: a powerful link between biological databases and microarray data analysis.Durinck, S., Moreau, Y., Kasprzyk, A., Davis, S., De Moor, B., Brazma, A., and Huber, W.
Bioinformatics (Oxford, England) 21, 3439-3440; 2005.
PubMedGenetic diversity in melanoma.Meltzer, P.S.
N Engl J Med 353, 2104-2107; 2005.
PubMedGene expression profiling of human sarcomas: insights into sarcoma biology.Baird, K., Davis, S., Antonescu, C.R., Harper, U.L., Walker, R.L., Chen, Y., Glatfelter, A.A., Duray, P.H., and Meltzer, P.S.
Cancer research 65, 9226-9235; 2005.
PubMedCancer genomics: small RNAs with big impacts.Meltzer, P.S.
Nature 435, 745-746; 2005.
PubMedStress-specific signatures: expression profiling of p53 wild-type and -null human cells.Amundson, S.A., Do, K.T., Vinikoor, L., Koch-Paiz, C.A., Bittner, M.L., Trent, J.M., Meltzer, P., and Fornace, A.J., Jr.
Oncogene 24, 4572-4579; 2005.
PubMedAn unliganded thyroid hormone beta receptor activates the cyclin D1/cyclin-dependent kinase/retinoblastoma/E2F pathway and induces pituitary tumorigenesis.Furumoto, H., Ying, H., Chandramouli, G.V., Zhao, L., Walker, R.L., Meltzer, P.S., Willingham, M.C., and Cheng, S.Y.
Molecular and cellular biology 25, 124-135; 2005.
PubMedThyroid hormone responsive genes in cultured human fibroblasts.Moeller, L.C., Dumitrescu, A.M., Walker, R.L., Meltzer, P.S., and Refetoff, S.
J Clin Endocrinol Metab 90, 936-943; 2005.
PubMedPim-1 is up-regulated by constitutively activated FLT3 and plays a role in FLT3-mediated cell survival.Kim, K.T., Baird, K., Ahn, J.Y., Meltzer, P., Lilly, M., Levis, M., and Small, D.
Blood 105, 1759-1767; 2005.
PubMedThree microarray platforms: an analysis of their concordance in profiling gene expression.Petersen, D., Chandramouli, G.V., Geoghegan, J., Hilburn, J., Paarlberg, J., Kim, C.H., Munroe, D., Gangi, L., Han, J., Puri, R., Staudt, L., Weinstein, J., Barrett, J.C., Green, J., and Kawasaki, E.S.
BMC genomics 6, 63; 2005.
PubMedNanotechnology, nanomedicine, and the development of new, effective therapies for cancer.Kawasaki, E.S., and Player, A.
Nanomedicine 1, 101-109; 2005.
PubMedCharacterizing dye bias in microarray experiments.Dobbin, K.K., Kawasaki, E.S., Petersen, D.W., and Simon, R.M.
Bioinformatics (Oxford, England) 21, 2430-2437; 2005.
PubMedThe External RNA Controls Consortium: a progress report.Baker, S.C., Bauer, S.R., Beyer, R.P., Brenton, J.D., Bromley, B., Burrill, J., Causton, H., Conley, M.P., Elespuru, R., Fero, M., Foy, C., Fuscoe, J., Gao, X., Gerhold, D.L., Gilles, P., Goodsaid, F., Guo, X., Hackett, J., Hockett, R.D., Ikonomi, P., Irizarry, R.A., Kawasaki, E.S., Kaysser-Kranich, T., Kerr, K., Kiser, G., Koch, W.H., Lee, K.Y., Liu, C., Liu, Z.L., Lucas, A., Manohar, C.F., Miyada, G., Modrusan, Z., Parkes, H., Puri, R.K., Reid, L., Ryder, T.B., Salit, M., Samaha, R.R., Scherf, U., Sendera, T.J., Setterquist, R.A., Shi, L., Shippy, R., Soriano, J.V., Wagar, E.A., Warrington, J.A., Williams, M., Wilmer, F., Wilson, M., Wolber, P.K., Wu, X., and Zadro, R.
Nat Methods 2, 731-734; 2005.
PubMedMultiple-laboratory comparison of microarray platforms.Irizarry, R.A., Warren, D., Spencer, F., Kim, I.F., Biswal, S., Frank, B.C., Gabrielson, E., Garcia, J.G., Geoghegan, J., Germino, G., Griffin, C., Hilmer, S.C., Hoffman, E., Jedlicka, A.E., Kawasaki, E., Martinez-Murillo, F., Morsberger, L., Lee, H., Petersen, D., Quackenbush, J., Scott, A., Wilson, M., Yang, Y., Ye, S.Q., and Yu, W.
Nat Methods 2, 345-350; 2005.
PubMedProposed methods for testing and selecting the ERCC external RNA controls.Consortium, E.R.C., Baker, S.C., ..., Kawasaki, E.S., ..., and Zadro, R.
BMC genomics 6, 150; 2005.
PubMedSerial analysis of gene expression during elongation of the peri-implantation porcine trophectoderm (conceptus).Blomberg, L.A., Long, E.L., Sonstegard, T.S., Van Tassell, C.P., Dobrinsky, J.R., and Zuelke, K.A.
Physiological genomics 20, 188-194; 2005.
PubMedHuman herpesvirus 8--a novel human pathogen.Edelman, D.C.
Virology journal 2, 78; 2005.
PubMedDetection of ultra-low levels of pathologic prion protein in scrapie infected hamster brain homogenates using real-time immuno-PCR.Barletta, J.M., Edelman, D.C., Highsmith, W.E., and Constantine, N.T.
Journal of virological methods 127, 154-164; 2005.
PubMedImmuno-PCR Method for the Detection of a Biomolecule in a Test Sample.Edelman, D.C.
PCT/WO2005/086647 A2 09/22/2005; 2005.
Frequent overexpression of ETS-related gene-1 (ERG1) in prostate cancer transcriptome.Petrovics, G., Liu, A., Shaheduzzaman, S., Furasato, B., Sun, C., Chen, Y., Nau, M., Ravindranath, L., Chen, Y., Dobi, A., Srikantan, V., Sesterhenn, I.A., McLeod, D.G., Vahey, M., Moul, J.W., and Srivastava, S.
Oncogene 24, 3847-3852; 2005.
PubMedChanges in gene expression during the development of mammary tumors in MMTV-Wnt-1 transgenic mice.Huang, S., Li, Y., Chen, Y., Podsypanina, K., Chamorro, M., Olshen, A.B., Desai, K.V., Tann, A., Petersen, D., Green, J.E., and Varmus, H.E.
Genome Biol 6, R84; 2005.
PubMedOptimal robust classifiers.Dougherty, E.R., Hua, J., Xiong, Z., and Chen, Y.
Pattern Recognition 38, 1520-1532; 2005.
PubMedMechanisms mediating the effects of prepubertal (n-3) polyunsaturated fatty acid diet on breast cancer risk in rats.Hilakivi-Clarke, L., Olivo, S.E., Shajahan, A., Khan, G., Zhu, Y., Zwart, A., Cho, E., and Clarke, R.
The Journal of nutrition 135, 2946S-2952S; 2005.
PubMedConversion of Fas-resistant to Fas-sensitive MCF-7 breast cancer cells by the synergistic interaction of interferon-gamma and all-trans retinoic acid.Danforth, D.N., and Zhu, Y.
Breast cancer research and treatment 94, 81-91; 2005.
PubMedInferring a tumor progression model for neuroblastoma from genomic data.Bilke, S., Chen, Q.R., Westerman, F., Schwab, M., Catchpoole, D., and Khan, J.
J Clin Oncol 23, 7322-7331; 2005.
PubMedHigh-resolution cDNA microarray-based comparative genomic hybridization analysis in neuroblastoma.Chen, Q.R., Bilke, S., and Khan, J.
Cancer letters 228, 71-81; 2005.
PubMedDatabase of mRNA gene expression profiles of multiple human organs.Son, C.G., Bilke, S., Davis, S., Greer, B.T., Wei, J.S., Whiteford, C.C., Chen, Q.R., Cenacchi, N., and Khan, J.
Genome research 15, 443-450; 2005.
PubMedAltered expression of cell cycle genes distinguishes aggressive neuroblastoma.Krasnoselsky, A.L., Whiteford, C.C., Wei, J.S., Bilke, S., Westermann, F., Chen, Q.R., and Khan, J.
Oncogene 24, 1533-1541; 2005.
PubMedDetection of low level genomic alterations by comparative genomic hybridization based on cDNA micro-arrays.Bilke, S., Chen, Q.R., Whiteford, C.C., and Khan, J.
Bioinformatics (Oxford, England) 21, 1138-1145; 2005.
PubMedGene expression profiling in breast cancer research.Meltzer, P.S.
Breast Dis 19, 23-27; 2004.
PubMedComparative genomic hybridization using oligonucleotide microarrays and total genomic DNA.Barrett, M.T., Scheffer, A., Ben-Dor, A., Sampas, N., Lipson, D., Kincaid, R., Tsang, P., Curry, B., Baird, K., Meltzer, P.S., Yakhini, Z., Bruhn, L., and Laderman, S.
Proceedings of the National Academy of Sciences of the United States of America 101, 17765-17770; 2004.
PubMedModulation of transcriptional sensitivity of mineralocorticoid and estrogen receptors.Wang, Q., Anzick, S., Richter, W.F., Meltzer, P., and Simons, S.S., Jr.
J Steroid Biochem Mol Biol 91, 197-210; 2004.
PubMedCloning and characterization of an inversion breakpoint at 6q23.3 suggests a role for Map7 in sacral dysgenesis.Sood, R., Bader, P.I., Speer, M.C., Edwards, Y.H., Eddings, E.M., Blair, R.T., Hu, P., Faruque, M.U., Robbins, C.M., Zhang, H., Leuders, J., Morrison, K., Thompson, D., Schwartzberg, P.L., Meltzer, P.S., and Trent, J.M.
Cytogenet Genome Res 106, 61-67; 2004.
PubMedIdentification of genes differentially regulated by the P210 BCR/ABL1 fusion oncogene using cDNA microarrays.Hakansson, P., Segal, D., Lassen, C., Gullberg, U., Morse, H.C., 3rd, Fioretos, T., and Meltzer, P.S.
Exp Hematol 32, 476-482; 2004.
PubMedFunctional genomics of UV radiation responses in human cells.Koch-Paiz, C.A., Amundson, S.A., Bittner, M.L., Meltzer, P.S., and Fornace, A.J., Jr.
Mutat Res 549, 65-78; 2004.
PubMedMicroarray expression profiling in melanoma reveals a BRAF mutation signature.Pavey, S., Johansson, P., Packer, L., Taylor, J., Stark, M., Pollock, P.M., Walker, G.J., Boyle, G.M., Harper, U., Cozzi, S.J., Hansen, K., Yudt, L., Schmidt, C., Hersey, P., Ellem, K.A., O'Rourke, M.G., Parsons, P.G., Meltzer, P., Ringner, M., and Hayward, N.K.
Oncogene 23, 4060-4067; 2004.
PubMedCDC91L1 (PIG-U) is a newly discovered oncogene in human bladder cancer.Guo, Z., Linn, J.F., Wu, G., Anzick, S.L., Eisenberger, C.F., Halachmi, S., Cohen, Y., Fomenkov, A., Hoque, M.O., Okami, K., Steiner, G., Engles, J.M., Osada, M., Moon, C., Ratovitski, E., Trent, J.M., Meltzer, P.S., Westra, W.H., Kiemeney, L.A., Schoenberg, M.P., Sidransky, D., and Trink, B.
Nat Med 10, 374-381; 2004.
PubMedPredicting continuous values of prognostic markers in breast cancer from microarray gene expression profiles.Gruvberger-Saal, S.K., Eden, P., Ringner, M., Baldetorp, B., Chebil, G., Borg, A., Ferno, M., Peterson, C., and Meltzer, P.S.
Mol Cancer Ther 3, 161-168; 2004.
PubMedGeneration and analysis of melanoma SAGE libraries: SAGE advice on the melanoma transcriptome.Weeraratna, A.T., Becker, D., Carr, K.M., Duray, P.H., Rosenblatt, K.P., Yang, S., Chen, Y., Bittner, M., Strausberg, R.L., Riggins, G.J., Wagner, U., Kallioniemi, O.P., Trent, J.M., Morin, P.J., and Meltzer, P.S.
Oncogene 23, 2264-2274; 2004.
PubMedMolecular and cellular determinants of estrogen receptor alpha expression.Pinzone, J.J., Stevenson, H., Strobl, J.S., and Berg, P.E.
Molecular and cellular biology 24, 4605-4612; 2004.
PubMedSAGE identification and fluorescence imaging analysis of genes and transcripts in melanomas and precursor lesions.Smith, A.P., Weeraratna, A.T., Spears, J.R., Meltzer, P.S., and Becker, D.
Cancer Biol Ther 3, 104-109; 2004.
PubMedExpression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators.Yu, Y., Khan, J., Khanna, C., Helman, L., Meltzer, P.S., and Merlino, G.
Nat Med 10, 175-181; 2004.
PubMedLaser capture microdissection, microarrays and the precise definition of a cancer cell.Player, A., Barrett, J.C., and Kawasaki, E.S.
Expert review of molecular diagnostics 4, 831-840; 2004.
PubMedMicroarrays and the gene expression profile of a single cell.Kawasaki, E.S.
Annals of the New York Academy of Sciences 1020, 92-100; 2004.
PubMedKinetic profiles of p300 occupancy in vivo predict common features of promoter structure and coactivator recruitment.Smith, J.L., Freebern, W.J., Collins, I., De Siervi, A., Montano, I., Haggerty, C.M., McNutt, M.C., Butscher, W.G., Dzekunova, I., Petersen, D.W., Kawasaki, E., Merchant, J.L., and Gardner, K.
Proceedings of the National Academy of Sciences of the United States of America 101, 11554-11559; 2004.
PubMedThe influence of dietary vitamin E, fat, and methionine on blood cholesterol profile, homocysteine levels, and oxidizability of low density lipoprotein in the gerbil.Hidiroglou, N., Gilani, G.S., Long, L., Zhao, X., Madere, R., Cockell, K., Belonge, B., Ratnayake, W.M., and Peace, R.
The Journal of nutritional biochemistry 15, 730-740; 2004.
PubMedA new superinvasive in vitro phenotype induced by selection of human breast carcinoma cells with the chemotherapeutic drugs paclitaxel and doxorubicin.Glynn, S.A., Gammell, P., Heenan, M., O'Connor, R., Liang, Y., Keenan, J., and Clynes, M.
British journal of cancer 91, 1800-1807; 2004.
PubMedEnhanced in vitro invasiveness and drug resistance with altered gene expression patterns in a human lung carcinoma cell line after pulse selection with anticancer drugs.Liang, Y., O'Driscoll, L., McDonnell, S., Doolan, P., Oglesby, I., Duffy, K., O'Connor, R., and Clynes, M.
International journal of cancer 111, 484-493; 2004.
PubMedTwo-deoxyglucose as an anti-metabolite in human carcinoma cell line RPMI-2650 and drug-resistant variants.Keenan, J., Liang, Y., and Clynes, M.
Anticancer research 24, 433-440; 2004.
PubMedLowering the detection limits of HIV-1 viral load using real-time immuno-PCR for HIV-1 p24 antigen.Barletta, J.M., Edelman, D.C., and Constantine, N.T.
American journal of clinical pathology 122, 20-27; 2004.
PubMedHigh-resolution analysis of gene copy number alterations in human prostate cancer using CGH on cDNA microarrays: impact of copy number on gene expression.Wolf, M., Mousses, S., Hautaniemi, S., Karhu, R., Huusko, P., Allinen, M., Elkahloun, A., Monni, O., Chen, Y., Kallioniemi, A., and Kallioniemi, O.P.
Neoplasia 6, 240-247; 2004.
PubMedDefective immune function of primary effusion lymphoma cells is associated with distinct KSHV gene expression profiles.Suscovich, T.J., Paulose-Murphy, M., Harlow, J.D., Chen, Y., Thomas, S.Y., Mellott, T.J., Walker, B.D., Scadden, D.T., Zeichner, S., and Brander, C.
Leuk Lymphoma 45, 1223-1238; 2004.
PubMedCancer-associated molecular signature in the tissue samples of patients with cirrhosis.Kim, J.W., Ye, Q., Forgues, M., Chen, Y., Budhu, A., Sime, J., Hofseth, L.J., Kaul, R., and Wang, X.W.
Hepatology 39, 518-527; 2004.
PubMedNonsense-mediated decay microarray analysis identifies mutations of EPHB2 in human prostate cancer.Huusko, P., Ponciano-Jackson, D., Wolf, M., Kiefer, J.A., Azorsa, D.O., Tuzmen, S., Weaver, D., Robbins, C., Moses, T., Allinen, M., Hautaniemi, S., Chen, Y., Elkahloun, A., Basik, M., Bova, G.S., Bubendorf, L., Lugli, A., Sauter, G., Schleutker, J., Ozcelik, H., Elowe, S., Pawson, T., Trent, J.M., Carpten, J.D., Kallioniemi, O.P., and Mousses, S.
Nat Genet 36, 979-983; 2004.
PubMedNoise factor analysis for cDNA microarrays.Balagurunathan, Y., Wang, N., Dougherty, E.R., Nguyen, D., Chen, Y., Bittner, M.L., Trent, J., and Carroll, R.
J Biomed Opt 9, 663-678; 2004.
PubMedWhich is better for cDNA-microarray-based classification: ratios or direct intensities.Attoor, S., Dougherty, E.R., Chen, Y., Bittner, M.L., and Trent, J.M.
Bioinformatics (Oxford, England) 20, 2513-2520; 2004.
PubMed|
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SupplementGene Expression Analysis via Multidimensional Scaling,.Chen, Y., and Meltzer, P.
In: Current Protocols. ; 2004.
A phase I study evaluating the safety, pharmacokinetics, and clinical response of a human IL-12 p40 antibody in subjects with plaque psoriasis.Kauffman, C.L., Aria, N., Toichi, E., McCormick, T.S., Cooper, K.D., Gottlieb, A.B., Everitt, D.E., Frederick, B., Zhu, Y., Graham, M.A., Pendley, C.E., and Mascelli, M.A.
The Journal of investigative dermatology 123, 1037-1044; 2004.
PubMedPrediction of clinical outcome using gene expression profiling and artificial neural networks for patients with neuroblastoma.Wei, J.S., Greer, B.T., Westermann, F., Steinberg, S.M., Son, C.G., Chen, Q.R., Whiteford, C.C., Bilke, S., Krasnoselsky, A.L., Cenacchi, N., Catchpoole, D., Berthold, F., Schwab, M., and Khan, J.
Cancer research 64, 6883-6891; 2004.
PubMedcDNA array-CGH profiling identifies genomic alterations specific to stage and MYCN-amplification in neuroblastoma.Chen, Q.R., Bilke, S., Wei, J.S., Whiteford, C.C., Cenacchi, N., Krasnoselsky, A.L., Greer, B.T., Son, C.G., Westermann, F., Berthold, F., Schwab, M., Catchpoole, D., and Khan, J.
BMC genomics 5, 70; 2004.
PubMedCorrelation of expression of BP1, a homeobox gene, with estrogen receptor status in breast cancer.Fu, S.W., Schwartz, A., Stevenson, H., Pinzone, J.J., Davenport, G.J., Orenstein, J.M., Gutierrez, P., Simmens, S.J., Abraham, J., Poola, I., Stephan, D.A., and Berg, P.E.
Breast Cancer Res 5, R82-87; 2003.
PubMedBiology of childhood osteogenic sarcoma and potential targets for therapeutic development: meeting summary.Gorlick, R., Anderson, P., Andrulis, I., Arndt, C., Beardsley, G.P., Bernstein, M., Bridge, J., Cheung, N.K., Dome, J.S., Ebb, D., Gardner, T., Gebhardt, M., Grier, H., Hansen, M., Healey, J., Helman, L., Hock, J., Houghton, J., Houghton, P., Huvos, A., Khanna, C., Kieran, M., Kleinerman, E., Ladanyi, M., Lau, C., Malkin, D., Marina, N., Meltzer, P., Meyers, P., Schofield, D., Schwartz, C., Smith, M.A., Toretsky, J., Tsokos, M., Wexler, L., Wigginton, J., Withrow, S., Schoenfeldt, M., and Anderson, B.
Clin Cancer Res 9, 5442-5453; 2003.
PubMedThe gene expression response of breast cancer to growth regulators: patterns and correlation with tumor expression profiles.Cunliffe, H.E., Ringner, M., Bilke, S., Walker, R.L., Cheung, J.M., Chen, Y., and Meltzer, P.S.
Cancer research 63, 7158-7166; 2003.
PubMedMutant thyroid hormone receptor beta represses the expression and transcriptional activity of peroxisome proliferator-activated receptor gamma during thyroid carcinogenesis.Ying, H., Suzuki, H., Zhao, L., Willingham, M.C., Meltzer, P., and Cheng, S.Y.
Cancer research 63, 5274-5280; 2003.
PubMedPhenotypic alterations in breast cancer cells overexpressing the nuclear receptor co-activator AIB1.Anzick, S.L., Azorsa, D.O., Simons, S.S., Jr., and Meltzer, P.S.
BMC Cancer 3, 22; 2003.
PubMedMechanisms of sarcoma development.Helman, L.J., and Meltzer, P.
Nat Rev Cancer 3, 685-694; 2003.
PubMedGene expression profile in multiple sclerosis patients and healthy controls: identifying pathways relevant to disease.Bomprezzi, R., Ringner, M., Kim, S., Bittner, M.L., Khan, J., Chen, Y., Elkahloun, A., Yu, A., Bielekova, B., Meltzer, P.S., Martin, R., McFarland, H.F., and Trent, J.M.
Hum Mol Genet 12, 2191-2199; 2003.
PubMedGene expression profiles in a panel of childhood leukemia cell lines mirror critical features of the disease.Kees, U.R., Ford, J., Watson, M., Murch, A., Ringner, M., Walker, R.L., and Meltzer, P.
Mol Cancer Ther 2, 671-677; 2003.
PubMedAlterations in genomic profiles during tumor progression in a mouse model of follicular thyroid carcinoma.Ying, H., Suzuki, H., Furumoto, H., Walker, R., Meltzer, P., Willingham, M.C., and Cheng, S.Y.
Carcinogenesis 24, 1467-1479; 2003.
PubMedSoft tissue sarcomas of adults: state of the translational science.Borden, E.C., Baker, L.H., Bell, R.S., Bramwell, V., Demetri, G.D., Eisenberg, B.L., Fletcher, C.D., Fletcher, J.A., Ladanyi, M., Meltzer, P., O'Sullivan, B., Parkinson, D.R., Pisters, P.W., Saxman, S., Singer, S., Sundaram, M., van Oosterom, A.T., Verweij, J., Waalen, J., Weiss, S.W., and Brennan, M.F.
Clin Cancer Res 9, 1941-1956; 2003.
PubMedEffects of ligand and thyroid hormone receptor isoforms on hepatic gene expression profiles of thyroid hormone receptor knockout mice.Yen, P.M., Feng, X., Flamant, F., Chen, Y., Walker, R.L., Weiss, R.E., Chassande, O., Samarut, J., Refetoff, S., and Meltzer, P.S.
EMBO Rep 4, 581-587; 2003.
PubMedMelanoma mouse model implicates metabotropic glutamate signaling in melanocytic neoplasia.Pollock, P.M., Cohen-Solal, K., Sood, R., Namkoong, J., Martino, J.J., Koganti, A., Zhu, H., Robbins, C., Makalowska, I., Shin, S.S., Marin, Y., Roberts, K.G., Yudt, L.M., Chen, A., Cheng, J., Incao, A., Pinkett, H.W., Graham, C.L., Dunn, K., Crespo-Carbone, S.M., Mackason, K.R., Ryan, K.B., Sinsimer, D., Goydos, J., Reuhl, K.R., Eckhaus, M., Meltzer, P.S., Pavan, W.J., Trent, J.M., and Chen, S.
Nat Genet 34, 108-112; 2003.
PubMedDifferential responses of stress genes to low dose-rate gamma irradiation.Amundson, S.A., Lee, R.A., Koch-Paiz, C.A., Bittner, M.L., Meltzer, P., Trent, J.M., and Fornace, A.J., Jr.
Mol Cancer Res 1, 445-452; 2003.
PubMedMolecular classification of familial non-BRCA1/BRCA2 breast cancer.Hedenfalk, I., Ringner, M., Ben-Dor, A., Yakhini, Z., Chen, Y., Chebil, G., Ach, R., Loman, N., Olsson, H., Meltzer, P., Borg, A., and Trent, J.
Proceedings of the National Academy of Sciences of the United States of America 100, 2532-2537; 2003.
PubMedMicroarray analysis of knockout mice identifies cyclin D2 as a possible mediator for the action of thyroid hormone during the postnatal development of the cerebellum.Poguet, A.L., Legrand, C., Feng, X., Yen, P.M., Meltzer, P., Samarut, J., and Flamant, F.
Dev Biol 254, 188-199; 2003.
PubMedExpression profiling to predict outcome in breast cancer: the influence of sample selection.Gruvberger, S.K., Ringner, M., Eden, P., Borg, A., Ferno, M., Peterson, C., and Meltzer, P.S.
Breast Cancer Res 5, 23-26; 2003.
PubMedActivating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins.Goo, Y.H., Sohn, Y.C., Kim, D.H., Kim, S.W., Kang, M.J., Jung, D.J., Kwak, E., Barlev, N.A., Berger, S.L., Chow, V.T., Roeder, R.G., Azorsa, D.O., Meltzer, P.S., Suh, P.G., Song, E.J., Lee, K.J., Lee, Y.C., and Lee, J.W.
Molecular and cellular biology 23, 140-149; 2003.
PubMedMicroarrays: the use of oligonucleotides and cDNA for the analysis of gene expression.Barrett, J.C., and Kawasaki, E.S.
Drug discovery today 8, 134-141; 2003.
PubMedHigh frequency of BRAF mutations in nevi.Pollock, P.M., Harper, U.L., Hansen, K.S., Yudt, L.M., Stark, M., Robbins, C.M., Moses, T.Y., Hostetter, G., Wagner, U., Kakareka, J., Salem, G., Pohida, T., Heenan, P., Duray, P., Kallioniemi, O., Hayward, N.K., Trent, J.M., and Meltzer, P.S.
Nat Genet 33, 19-20; 2003.
PubMedInhibition of Moloney murine leukemia virus integration using polyamides targeting the long-terminal repeat sequences.Yang, F., Belitsky, J.M., Villanueva, R.A., Dervan, P.B., and Roth, M.J.
Biochemistry 42, 6249-6258; 2003.
PubMedLactation persistency: insights from mammary cell proliferation studies.Capuco, A.V., Ellis, S.E., Hale, S.A., Long, E., Erdman, R.A., Zhao, X., and Paape, M.J.
Journal of animal science 81 Suppl 3, 18-31; 2003.
PubMedSerial analysis of gene expression in turkey sperm storage tubules in the presence and absence of resident sperm.Long, E.L., Sonstegard, T.S., Long, J.A., Van Tassell, C.P., and Zuelke, K.A.
Biology of reproduction 69, 469-474; 2003.
PubMedReal-time PCR provides improved detection and titer determination of bacteriophage.Edelman, D.C., and Barletta, J.
BioTechniques 35, 368-375; 2003.
PubMedUltra-low detection of HIV p24 in patient samples using immuno-PCR (I-PCR).Barletta, J., Edelman, D., and Constantine, N.T.
Proceedings of the 8th World STI/AIDS Congress, Punta del Este, Uruguay. ; 2003.
Prevalence of hepatitis G virus infection in a convenience sample of dental hygienists.Wisnom, C., DeVore, L.R., Macek, M.D., Constantine, N.T., DePaola, L.G., Saville, R., Edelman, D., Ketema, F., and Falkler, W.
J Dental Hygiene 77, 54-55; 2003.
Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning.Ye, Q.H., Qin, L.X., Forgues, M., He, P., Kim, J.W., Peng, A.C., Simon, R., Li, Y., Robles, A.I., Chen, Y., Ma, Z.C., Wu, Z.Q., Ye, S.L., Liu, Y.K., Tang, Z.Y., and Wang, X.W.
Nat Med 9, 416-423; 2003.
PubMedErratum: Expression profiling of medulloblastoma: PDGFRA and the RAS/MAPK pathway as therapeutic targets for metastatic disease (Nature Genetics (2001) 29(143-152)).MacDonald, T.J., Brown, K.M., LaFleur, B., Peterson, K., Lawlor, C., Chen, Y., Packer, R.J., Cogen, P., and Stephan, D.A.
Nature Genetics 35, 287; 2003.
PubMedThe Gene Expression Response of Breast Cancer to Growth Regulators: Patterns and Correlation with Tumor Expression Profiles.Cunliffe, H.E., Ringne?r, M., Bilke, S., Walker, R.L., Cheung, J.M., Chen, Y., and Meltzer, P.S.
Cancer research 63, 7158-7166; 2003.
PubMedGene expression profile in multiple sclerosis patients and healthy controls: Identifying pathways relevant to disease.Bomprezzi, R., Ringne?r, M., Kim, S., Bittner, M.L., Khan, J., Chen, Y., Elkahloun, A., Yu, A., Bielekova, B., Meltzer, P.S., Martin, R., McFarland, H.F., and Trent, J.M.
Human Molecular Genetics 12, 2191-2199; 2003.
PubMedProbe generation directly from small numbers of cells for DNA microarray studies.Xiang, C.C., Chen, M., Kozhich, O.A., Phan, Q.N., Inman, J.M., Chen, Y., and Brownstein, M.J.
BioTechniques 34, 386-393; 2003.
PubMedAntiestrogen resistance in breast cancer and the role of estrogen receptor signaling.Clarke, R., Liu, M.C., Bouker, K.B., Gu, Z., Lee, R.Y., Zhu, Y., Skaar, T.C., Gomez, B., O'Brien, K., Wang, Y., and Hilakivi-Clarke, L.A.
Oncogene 22, 7316-7339; 2003.
PubMedProbabilistic estimation of microarray data reliability and underlying gene expression.Bilke, S., Breslin, T., and Sigvardsson, M.
BMC bioinformatics 4, 40; 2003.
PubMedRNA analysis of B cell lines arrested at defined stages of differentiation allows for an approximation of gene expression patterns during B cell development.Tsapogas, P., Breslin, T., Bilke, S., Lagergren, A., Mansson, R., Liberg, D., Peterson, C., and Sigvardsson, M.
Journal of leukocyte biology 74, 102-110; 2003.
PubMedCD44-stimulated human B cells express transcripts specifically involved in immunomodulation and inflammation as analyzed by DNA microarrays.Hogerkorp, C.M., Bilke, S., Breslin, T., Ingvarsson, S., and Borrebaeck, C.A.
Blood 101, 2307-2313; 2003.
PubMedWnt5a signaling directly affects cell motility and invasion of metastatic melanoma.Weeraratna, A.T., Jiang, Y., Hostetter, G., Rosenblatt, K., Duray, P., Bittner, M., and Trent, J.M.
Cancer Cell 1, 279-288; 2002.
PubMedMutation of melanosome protein RAB38 in chocolate mice.Loftus, S.K., Larson, D.M., Baxter, L.L., Antonellis, A., Chen, Y., Wu, X., Jiang, Y., Bittner, M., Hammer, J.A., 3rd, and Pavan, W.J.
Proceedings of the National Academy of Sciences of the United States of America 99, 4471-4476; 2002.
PubMedBP1, a homeodomain-containing isoform of DLX4, represses the beta-globin gene.Chase, M.B., Fu, S., Haga, S.B., Davenport, G., Stevenson, H., Do, K., Morgan, D., Mah, A.L., and Berg, P.E.
Molecular and cellular biology 22, 2505-2514; 2002.
PubMedExpression profiling of synovial sarcoma by cDNA microarrays: association of ERBB2, IGFBP2, and ELF3 with epithelial differentiation.Allander, S.V., Illei, P.B., Chen, Y., Antonescu, C.R., Bittner, M., Ladanyi, M., and Meltzer, P.S.
Am J Pathol 161, 1587-1595; 2002.
PubMedExpression of multiple molecular phenotypes by aggressive melanoma tumor cells: role in vasculogenic mimicry.Seftor, E.A., Meltzer, P.S., Schatteman, G.C., Gruman, L.M., Hess, A.R., Kirschmann, D.A., Seftor, R.E., and Hendrix, M.J.
Crit Rev Oncol Hematol 44, 17-27; 2002.
PubMedFocus on sarcomas.Mackall, C.L., Meltzer, P.S., and Helman, L.J.
Cancer Cell 2, 175-178; 2002.
PubMedRatio statistics of gene expression levels and applications to microarray data analysis.Chen, Y., Kamat, V., Dougherty, E.R., Bittner, M.L., Meltzer, P.S., and Trent, J.M.
Bioinformatics (Oxford, England) 18, 1207-1215; 2002.
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SupplementHuman AML cells in NOD/SCID mice: engraftment potential and gene expression.Lumkul, R., Gorin, N.C., Malehorn, M.T., Hoehn, G.T., Zheng, R., Baldwin, B., Small, D., Gore, S., Smith, D., Meltzer, P.S., and Civin, C.I.
Leukemia 16, 1818-1826; 2002.
PubMedA genome-based strategy uncovers frequent BRAF mutations in melanoma.Pollock, P.M., and Meltzer, P.S.
Cancer Cell 2, 5-7; 2002.
PubMedTransgenic targeting of a dominant negative corepressor to liver and analyses by cDNA microarray.Feng, X., Meltzer, P., and Yen, P.M.
Methods in molecular biology (Clifton, NJ 202, 31-54; 2002.
PubMedLucky draw in the gene raffle.Pollock, P.M., and Meltzer, P.S.
Nature 417, 906-907; 2002.
PubMedMolecular determinants of human uveal melanoma invasion and metastasis.Seftor, E.A., Meltzer, P.S., Kirschmann, D.A., Pe'er, J., Maniotis, A.J., Trent, J.M., Folberg, R., and Hendrix, M.J.
Clin Exp Metastasis 19, 233-246; 2002.
PubMedGene expression profiling in cancer using cDNA microarrays.Khan, J., Saal, L.H., Bittner, M.L., Jiang, Y., Gooden, G.C., Glatfelter, A.A., and Meltzer, P.S.
Methods Mol Med 68, 205-222; 2002.
PubMedStress-gene induction by low-dose gamma irradiation.Fornace, A.J., Jr., Amundson, S.A., Do, K.T., Meltzer, P., Trent, J., and Bittner, M.
Mil Med 167, 13-15; 2002.
PubMedEffects of HIV-1 Nef on cellular gene expression profiles.Shaheduzzaman, S., Krishnan, V., Petrovic, A., Bittner, M., Meltzer, P., Trent, J., Venkatesan, S., and Zeichner, S.
J Biomed Sci 9, 82-96; 2002.
PubMedGermline mutations in the ribonuclease L gene in families showing linkage with HPC1.Carpten, J., Nupponen, N., Isaacs, S., Sood, R., Robbins, C., Xu, J., Faruque, M., Moses, T., Ewing, C., Gillanders, E., Hu, P., Bujnovszky, P., Makalowska, I., Baffoe-Bonnie, A., Faith, D., Smith, J., Stephan, D., Wiley, K., Brownstein, M., Gildea, D., Kelly, B., Jenkins, R., Hostetter, G., Matikainen, M., Schleutker, J., Klinger, K., Connors, T., Xiang, Y., Wang, Z., De Marzo, A., Papadopoulos, N., Kallioniemi, O.P., Burk, R., Meyers, D., Gronberg, H., Meltzer, P., Silverman, R., Bailey-Wilson, J., Walsh, P., Isaacs, W., and Trent, J.
Nat Genet 30, 181-184; 2002.
PubMedGalectin-3 expression alters adhesion, motility and invasion in a lung cell line (DLKP), in vitro.O'Driscoll, L., Linehan, R., Liang, Y.H., Joyce, H., Oglesby, I., and Clynes, M.
Anticancer research 22, 3117-3125; 2002.
PubMedExamining the relationship between cancer invasion/metastasis and drug resistance.Liang, Y., McDonnell, S., and Clynes, M.
Current cancer drug targets 2, 257-277; 2002.
PubMedHepatitis C virus transfusion-transmitted infection in Brazilian cardiac surgery patients.Nogueira, C.A., Edelman, D.C., Nogueira, C.M., Nogueira, S.A., Coelho, H.S., Abrahao, L.J., Vanderboght, B., Lambert, J.S., and Constantine, N.T.
Clinical laboratory 48, 529-533; 2002.
PubMedA lack of clinical correlation between the presence of HHV-8 DNA in PBMCs and staging of Kaposi's sarcoma.Edelman, D.C., and Sill, A.
Dermatology (Basel, Switzerland) 205, 189; 2002.
PubMedStrong feature sets from small samples.Kim, S., Dougherty, E.R., Barrera, J., Chen, Y., Bittner, M.L., and Trent, J.M.
J Comput Biol 9, 127-146; 2002.
PubMed |
PDFInference from clustering with application to gene-expression microarrays.Dougherty, E.R., Barrera, J., Brun, M., Kim, S., Cesar, R.M., Chen, Y., Bittner, M., and Trent, J.M.
J Comput Biol 9, 105-126; 2002.
PubMed |
PDFSimulation of cDNA microarrays via a parameterized random signal model.Balagurunathan, Y., Dougherty, E.R., Chen, Y., Bittner, M.L., and Trent, J.M.
J Biomed Opt 7, 507-523; 2002.
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SupplementGene expression signature of benign prostatic hyperplasia revealed by cDNA microarray analysis.Luo, J., Dunn, T., Ewing, C., Sauvageot, J., Chen, Y., Trent, J., and Isaacs, W.
Prostate 51, 189-200; 2002.
PubMedCan Markov chain models mimic biological regulation?Kim, S., Li, H., Dougherty, E.R., Cao, N., Chen, Y., Bittner, M., and Suh, E.B.
Journal of Biological Systems 10, 337-357; 2002.
PubMed |
PDFGene expression after treatment with hydrogen peroxide, menadione, or t-butyl hydroperoxide in breast cancer cells.Chuang, Y.Y.E., Chen, Y., Chandramouli, G.V.R., Cook, J.A., Coffin, D., Tsai, M.H., DeGraff, W., Yan, H., Zhao, S., Russo, A., Liu, E.T., and Mitchell, J.B.
Cancer research 62, 6246-6254; 2002.
PubMed |
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SupplementAssessing the significance of consistently mis-regulated genes in cancer associated gene expression matrices.Wahde, M., Klus, G.T., Bittner, M.L., Chen, Y., and Szallasi, Z.
Bioinformatics (Oxford, England) 18, 389-394; 2002.
PubMed |
PDFAmine-modified random primers to label probes for DNA microarrays.Xiang, C.C., Kozhich, O.A., Chen, M., Inman, J.M., Phan, Q.N., Chen, Y., and Brownstein, M.J.
Nature biotechnology 20, 738-742; 2002.
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Microarray Image Analysis and Gene Expression Ratio Statistics.Chen, Y., Dougherty, E.R., Bittner, M., Meleady, P., and Trent, J.
In: Computational And Statistical Approaches To Genomics. Kluwer, ; 2002.
DNA Array Manual.Chen, Y.
In: DNA Array Manual. ColdSpring Harbor Press, ; 2002.
Role of genomics in identifying new targets for cancer therapy.Anzick, S.L., and Trent, J.M.
Oncology (Williston Park, NY 16, 7-13; 2002.
PubMedAssociation of interferon regulatory factor-1, nucleophosmin, nuclear factor-kappaB, and cyclic AMP response element binding with acquired resistance to Faslodex (ICI 182,780).Gu, Z., Lee, R.Y., Skaar, T.C., Bouker, K.B., Welch, J.N., Lu, J., Liu, A., Zhu, Y., Davis, N., Leonessa, F., Brunner, N., Wang, Y., and Clarke, R.
Cancer research 62, 3428-3437; 2002.
PubMedEarly B-cell factor, E2A, and Pax-5 cooperate to activate the early B cell-specific mb-1 promoter.Sigvardsson, M., Clark, D.R., Fitzsimmons, D., Doyle, M., Akerblad, P., Breslin, T., Bilke, S., Li, R., Yeamans, C., Zhang, G., and Hagman, J.
Molecular and cellular biology 22, 8539-8551; 2002.
PubMedStability of the Kauffman model.Bilke, S., and Sjunnesson, F.
Physical review 65, 016129; 2002.
PubMedImpact of overlapping recruitment on linkage analysis of complex disorders: simulation studies.Davis, S., and Nimgaonkar, V.L.
Am J Med Genet 105, 141-144; 2001.
PubMedProfiling Human Gene Expression with cDNA Microarrays.Jiang, Y., Lueders, J., Glatfelter, A., Gooden, C., and Bittner, M.
In: Current Protocols in Molecular Biology John Wiley & Sons, Inc., 22.23.21-22.23.26; 2001.
Distinct functions of two isoforms of a homeobox gene, BP1 and DLX7, in the regulation of the beta-globin gene.Fu, S., Stevenson, H., Strovel, J.W., Haga, S.B., Stamberg, J., Do, K., and Berg, P.E.
Gene 278, 131-139; 2001.
PubMedMutational analysis of the N-terminus of Moloney murine leukemia virus integrase.Yang, F., Seamon, J.A., and Roth, M.J.
Virology 291, 32-45; 2001.
PubMedAssembly and catalysis of concerted two-end integration events by Moloney murine leukemia virus integrase.Yang, F., and Roth, M.J.
Journal of virology 75, 9561-9570; 2001.
PubMedBiological indicators for the identification of ionizing radiation exposure in humans.Amundson, S.A., Bittner, M., Meltzer, P., Trent, J., and Fornace, A.J., Jr.
Expert review of molecular diagnostics 1, 211-219; 2001.
PubMedCloning of bovine eukaryotic translation initiation factor 4E (eIF-4E) and its expression in the bovine mammary gland at different physiological stages.Long, E., Capuco, A.V., and Zhao, X.
DNA Seq 12, 319-329; 2001.
PubMedEscherichia coli induces apoptosis and proliferation of mammary cells.Long, E., Capuco, A.V., Wood, D.L., Sonstegard, T., Tomita, G., Paape, M.J., and Zhao, X.
Cell death and differentiation 8, 808-816; 2001.
PubMedAssociation of steroid receptor coactivator AIB1 with estrogen receptor-alpha in breast cancer cells.Azorsa, D.O., Cunliffe, H.E., and Meltzer, P.S.
Breast cancer research and treatment 70, 89-101; 2001.
PubMedOverexpressing eukaryotic translation initiation factor 4E stimulates bovine mammary epithelial cell proliferation.Long, E., Lazaris-Karatzas, A., Karatzas, C., and Zhao, X.
The international journal of biochemistry & cell biology 33, 133-141; 2001.
PubMedGastrointestinal stromal tumors with KIT mutations exhibit a remarkably homogeneous gene expression profile.Allander, S.V., Nupponen, N.N., Ringner, M., Hostetter, G., Maher, G.W., Goldberger, N., Chen, Y., Carpten, J., Elkahloun, A.G., and Meltzer, P.S.
Cancer research 61, 8624-8628; 2001.
PubMedApplication of molecular cytogenetic techniques in a case study of human cutaneous metastatic melanoma.Wiltshire, R.N., Dennis, T.R., Sondak, V.K., Meltzer, P.S., and Trent, J.M.
Cancer Genet Cytogenet 131, 97-103; 2001.
PubMedDetection of antisense and ribozyme accessible sites on native mRNAs: application to NCOA3 mRNA.Scherr, M., LeBon, J., Castanotto, D., Cunliffe, H.E., Meltzer, P.S., Ganser, A., Riggs, A.D., and Rossi, J.J.
Mol Ther 4, 454-460; 2001.
PubMedDisease fingerprinting with cDNA microarrays reveals distinct gene expression profiles in lethal type 1 and type 2 cytokine-mediated inflammatory reactions.Hoffmann, K.F., McCarty, T.C., Segal, D.H., Chiaramonte, M., Hesse, M., Davis, E.M., Cheever, A.W., Meltzer, P.S., Morse, H.C., 3rd, and Wynn, T.A.
Faseb J 15, 2545-2547; 2001.
PubMedInduction of gene expression as a monitor of exposure to ionizing radiation.Amundson, S.A., Bittner, M., Meltzer, P., Trent, J., and Fornace, A.J., Jr.
Radiation research 156, 657-661; 2001.
PubMedCooperative interactions of laminin 5 gamma2 chain, matrix metalloproteinase-2, and membrane type-1-matrix/metalloproteinase are required for mimicry of embryonic vasculogenesis by aggressive melanoma.Seftor, R.E., Seftor, E.A., Koshikawa, N., Meltzer, P.S., Gardner, L.M., Bilban, M., Stetler-Stevenson, W.G., Quaranta, V., and Hendrix, M.J.
Cancer research 61, 6322-6327; 2001.
PubMedEstrogen receptor status in breast cancer is associated with remarkably distinct gene expression patterns.Gruvberger, S., Ringner, M., Chen, Y., Panavally, S., Saal, L.H., Borg, A., Ferno, M., Peterson, C., and Meltzer, P.S.
Cancer research 61, 5979-5984; 2001.
PubMedGenome-wide expression changes induced by HTLV-1 Tax: evidence for MLK-3 mixed lineage kinase involvement in Tax-mediated NF-kappaB activation.Ng, P.W., Iha, H., Iwanaga, Y., Bittner, M., Chen, Y., Jiang, Y., Gooden, G., Trent, J.M., Meltzer, P., Jeang, K.T., and Zeichner, S.L.
Oncogene 20, 4484-4496; 2001.
PubMedTwo-dimensional DNA electrophoresis identifies novel CpG islands frequently coamplified with MYCN in neuroblastoma.Wimmer, K., Zhu, X.X., Lamb, B.J., Kuick, R., Ambros, P., Kovar, H., Thoraval, D., Elkahloun, A., Meltzer, P., and Hanash, S.M.
Med Pediatr Oncol 36, 75-79; 2001.
PubMedSelection with melphalan or paclitaxel (Taxol) yields variants with different patterns of multidrug resistance, integrin expression and in vitro invasiveness.Liang, Y., Meleady, P., Cleary, I., McDonnell, S., Connolly, L., and Clynes, M.
Eur J Cancer 37, 1041-1052; 2001.
PubMedLarge-scale genome analysis.Meltzer, P.S.
Methods Biochem Anal 43, 393-412; 2001.
PubMedPhysiological function as regulation of large transcriptional programs: the cellular response to genotoxic stress.Amundson, S.A., Bittner, M., Meltzer, P., Trent, J., and Fornace, A.J., Jr.
Comp Biochem Physiol B Biochem Mol Biol 129, 703-710; 2001.
PubMedExpression and functional significance of VE-cadherin in aggressive human melanoma cells: role in vasculogenic mimicry.Hendrix, M.J., Seftor, E.A., Meltzer, P.S., Gardner, L.M., Hess, A.R., Kirschmann, D.A., Schatteman, G.C., and Seftor, R.E.
Proceedings of the National Academy of Sciences of the United States of America 98, 8018-8023; 2001.
PubMedClassification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks.Khan, J., Wei, J.S., Ringner, M., Saal, L.H., Ladanyi, M., Westermann, F., Berthold, F., Schwab, M., Antonescu, C.R., Peterson, C., and Meltzer, P.S.
Nat Med 7, 673-679; 2001.
PubMedSpotting the target: microarrays for disease gene discovery.Meltzer, P.S.
Curr Opin Genet Dev 11, 258-263; 2001.
PubMedTransgenic targeting of a dominant negative corepressor to liver blocks basal repression by thyroid hormone receptor and increases cell proliferation.Feng, X., Jiang, Y., Meltzer, P., and Yen, P.M.
The Journal of biological chemistry 276, 15066-15072; 2001.
PubMedMetastasis-associated differences in gene expression in a murine model of osteosarcoma.Khanna, C., Khan, J., Nguyen, P., Prehn, J., Caylor, J., Yeung, C., Trepel, J., Meltzer, P., and Helman, L.
Cancer research 61, 3750-3759; 2001.
PubMedThe incidence of GB virus C / hepatitis G virus infection in Brazilian patients who received blood transfusion during cardiac surgery.Villela Nogueira, C.A., Nogueira, S.A., Nogueira, C.N., Coelho, H.S., Ketema, F., Edelman, D.C., Lambert, J.S., and Constantine, N.T.
Journal of medical virology 63, 237-241; 2001.
PubMedTranscription program of human herpesvirus 8 (kaposi's sarcoma-associated herpesvirus).Paulose-Murphy, M., Ha, N.K., Xiang, C., Chen, Y., Gillim, L., Yarchoan, R., Meltzer, P., Bittner, M., Trent, J., and Zeichner, S.
Journal of virology 75, 4843-4853; 2001.
PubMedAssessment of the performance of a rapid, lateral flow assay for the detection of antibodies to HIV.Ketema, F., Zeh, C., Edelman, D.C., Saville, R., and Constantine, N.T.
Journal of acquired immune deficiency syndromes (1999) 27, 63-70; 2001.
PubMedGene-expression profiles in hereditary breast cancer.Hedenfalk, I., Duggan, D., Chen, Y., Radmacher, M., Bittner, M., Simon, R., Meltzer, P., Gusterson, B., Esteller, M., Kallioniemi, O.P., Wilfond, B., Borg, A., Trent, J., Raffeld, M., Yakhini, Z., Ben-Dor, A., Dougherty, E., Kononen, J., Bubendorf, L., Fehrle, W., Pittaluga, S., Gruvberger, S., Loman, N., Johannsson, O., Olsson, H., and Sauter, G.
N Engl J Med 344, 539-548; 2001.
PubMedNegative human herpesvirus 8 serology in sarcoidosis.Haburchak, D.R., Thomason, J.W., Edelman, D.C., and Constantine, N.T.
Journal of human virology 4, 111; 2001.
PubMedChromosome arm-specific multicolor FISH.Karhu, R., Ahlstedt-Soini, M., Bittner, M., Meltzer, P., Trent, J.M., and Isola, J.J.
Genes, chromosomes & cancer 30, 105-109; 2001.
PubMedFailure of hormone therapy in prostate cancer involves systematic restoration of androgen responsive genes and activation of rapamycin sensitive signaling.Mousses, S., Wagner, U., Chen, Y., Kim, J.W., Bubendorf, L., Bittner, M., Pretlow, T., Elkahloun, A.G., Trepel, J.B., and Kallioniemi, O.P.
Oncogene 20, 6718-6723; 2001.
PubMedComprehensive copy number and gene expression profiling of the 17q23 amplicon in human breast cancer.Monni, O., Barlund, M., Mousses, S., Kononen, J., Sauter, G., Heiskanen, M., Paavola, P., Avela, K., Chen, Y., Bittner, M.L., and Kallioniemi, A.
Proceedings of the National Academy of Sciences of the United States of America 98, 5711-5716; 2001.
PubMedGastrointestinal stromal tumors with KIT mutations exhibit a remarkably homogeneous gene expression profile.Allander, S.V., Nupponen, N.N., Ringne?r, M., Hostetter, G., Maher, G.W., Goldberger, N., Chen, Y., Carpten, J., Elkahloun, A.G., and Meltzer, P.S.
Cancer research 61, 8624-8628; 2001.
PubMedEstrogen receptor status in breast cancer is associated with remarkably distinct gene expression patterns.Gruvberger, S., Ringne?r, M., Chen, Y., Panavally, S., Saal, L.H., Borg, A., Ferno, M., Peterson, C., and Meltzer, P.S.
Cancer research 61, 5979-5984; 2001.
PubMedDown-regulation of the desmosomal cadherin desmocollin 3 in human breast cancer.Klus, G.T., Rokaeus, N., Bittner, M.L., Chen, Y., Korz, D.M., Sukumar, S., Schick, A., and Szallasi, Z.
International journal of oncology 19, 169-174; 2001.
PubMedHuman prostate cancer and benign prostatic hyperplasia: Molecular dissection by gene expression profiling.Luo, J., Duggan, D.J., Chen, Y., Sauvageot, J., Ewing, C.M., Bittner, M.L., Trent, J.M., and Isaacs, W.B.
Cancer research 61, 4683-4688; 2001.
PubMedGene-expression profiles in hereditary breast cancer.Hedenfalk, I., Duggan, D., Chen, Y., Radmatcher, M., Bittner, M., Simon, R., Meltzer, P., Gusterson, B., Esteller, M., Kallioniemi, O.P., Wilfond, B., Borg, A., and Trent, J.
New England Journal of Medicine 344, 539-548; 2001.
PubMedAnalysis of expression patterns: The scope of the problem, the problem of scope.Chen, Y., Yakhini, Z., Ben-Dor, A., Dougherty, E., Trent, J.M., and Bittner, M.
Disease Markers 17, 59-65; 2001.
PubMedErratum: Molecular classification of cutaneous malignant melanoma by gene expression profiling. (Nature (2000) vol. 406 (536-540)).Bittner, M., Meltzer, P., and Chen, Y.
Oncology Spectrums 2, 307; 2001.
PubMedExpression profiling of medulloblastoma: PDGFRA and the RAS/MAPK pathway as therapeutic targets for metastatic disease.MacDonald, T.J., Brown, K.M., LaFleur, B., Peterson, K., Lawlor, C., Chen, Y., Packer, R.J., Cogen, P., and Stephan, D.A.
Nature Genetics 29, 143-152; 2001.
PubMedFinding robust linear expression-based classifiers.Kim, S., Dougherty, E.R., Barrera, J., Chen, Y., Bittner, M., and Trent, J.M.
Proceedings of SPIE - The International Society for Optical Engineering,Location ; 2001.
Topological properties of citation and metabolic networks.Bilke, S., and Peterson, C.
Physical review 64, 036106; 2001.
PubMedIdentification of tumor-suppressor genes using human melanoma cell lines UACC903, UACC903(+6), and SRS3 by comparison of expression profiles.Su, Y.A., Bittner, M.L., Chen, Y., Tao, L., Jiang, Y., Zhang, Y., Stephan, D.A., and Trent, J.M.
Molecular carcinogenesis 28, 119-127; 2000.
PubMedComparative genomic hybridization analysis of 38 breast cancer cell lines: a basis for interpreting complementary DNA microarray data.Forozan, F., Mahlamaki, E.H., Monni, O., Chen, Y., Veldman, R., Jiang, Y., Gooden, G.C., Ethier, S.P., Kallioniemi, A., and Kallioniemi, O.P.
Cancer research 60, 4519-4525; 2000.
PubMedProfiling Human Gene Expression with cDNA Microarrays.Jiang, Y., Lueders, J., Glatfelter, A., Gooden, C., and Bittner, M.
In: Current Protocols in Human Genetics. John Wiley & Sons, Inc., 11.13.11-11.13.26; 2000.
Lipid peroxidation is associated with the inhibitory action of all-trans-retinoic acid on mammary cell transformation.Kubow, S., Woodward, T.L., Turner, J.D., Nicodemo, A., Long, E., and Zhao, X.
Anticancer research 20, 843-848; 2000.
PubMedDetection of Kaposi's sarcoma-associated herpesvirus in oral and genital secretions of Zimbabwean women.Lampinen, T.M., Kulasingam, S., Min, J., Borok, M., Gwanzura, L., Lamb, J., Mahomed, K., Woelk, G.B., Strand, K.B., Bosch, M.L., Edelman, D.C., Constantine, N.T., Katzenstein, D., and Williams, M.A.
The Journal of infectious diseases 181, 1785-1790; 2000.
PubMedGeneral nonlinear framework for the analysis of gene interaction via multivariate expression arrays.Kim, S., Dougherty, E.R., Bittner, M.L., Chen, Y., Sivakumar, K., Meltzer, P., and Trent, J.M.
J Biomed Opt 5, 411-424; 2000.
PubMed |
PDFSpecifics on the refinement and application of two serological assays for the detection of antibodies to HHV-8.Edelman, D.C., Ketema, F., Saville, R.D., Herman, J., Sill, A.M., Gill, P.S., Blattner, W.A., and Constantine, N.T.
J Clin Virol 16, 225-237; 2000.
PubMedAlleles of the estrogen receptor alpha-gene and an estrogen receptor cotranscriptional activator gene, amplified in breast cancer-1 (AIB1), are associated with quantitative calcaneal ultrasound.Patel, M.S., Cole, D.E., Smith, J.D., Hawker, G.A., Wong, B., Trang, H., Vieth, R., Meltzer, P., and Rubin, L.A.
J Bone Miner Res 15, 2231-2239; 2000.
PubMedEndogenously expressed estrogen receptor and coactivator AIB1 interact in MCF-7 human breast cancer cells.Tikkanen, M.K., Carter, D.J., Harris, A.M., Le, H.M., Azorsa, D.O., Meltzer, P.S., and Murdoch, F.E.
Proceedings of the National Academy of Sciences of the United States of America 97, 12536-12540; 2000.
PubMedIdentification of potential mRNA biomarkers in peripheral blood lymphocytes for human exposure to ionizing radiation.Amundson, S.A., Do, K.T., Shahab, S., Bittner, M., Meltzer, P., Trent, J., and Fornace, A.J., Jr.
Radiation research 154, 342-346; 2000.
PubMedMolecular classification of cutaneous malignant melanoma by gene expression profiling.Bittner, M., Meltzer, P., Chen, Y., Jiang, Y., Seftor, E., Hendrix, M., Radmacher, M., Simon, R., Yakhini, Z., Ben-Dor, A., Sampas, N., Dougherty, E., Wang, E., Marincola, F., Gooden, C., Lueders, J., Glatfelter, A., Pollock, P., Carpten, J., Gillanders, E., Leja, D., Dietrich, K., Beaudry, C., Berens, M., Alberts, D., and Sondak, V.
Nature 406, 536-540; 2000.
PubMedMonitoring the expression profiles of doxorubicin-induced and doxorubicin-resistant cancer cells by cDNA microarray.Kudoh, K., Ramanna, M., Ravatn, R., Elkahloun, A.G., Bittner, M.L., Meltzer, P.S., Trent, J.M., Dalton, W.S., and Chin, K.V.
Cancer research 60, 4161-4166; 2000.
PubMedStructure and promoter analysis of the human unc-33-like phosphoprotein gene: E-box required for maximal expression in neuroblastoma and myoblasts.Matsuo, T., Stauffer, J.K., Walker, R.L., Meltzer, P., and Thiele, C.J.
The Journal of biological chemistry 275, 25052; 2000.
PubMedMultivariate measurement of gene expression relationships.Kim, S., Dougherty, E.R., Chen, Y., Sivakumar, K., Meltzer, P., Trent, J.M., and Bittner, M.
Genomics 67, 201-209; 2000.
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PDFThyroid hormone regulation of hepatic genes in vivo detected by complementary DNA microarray.Feng, X., Jiang, Y., Meltzer, P., and Yen, P.M.
Molecular endocrinology (Baltimore, Md 14, 947-955; 2000.
PubMedIdentification of a larger than 3 Mb dele